Toxic Epidermal Necrolysis Induced by the Topical Carbonic Anhydrase Inhibitors Brinzolamide and Dorzolamide
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Toxic Epidermal Necrolysis Induced by the Topical Carbonic Anhydrase Inhibitors Brinzolamide and Dorzolamide.
Brinzolamide and dorzolamide are highly specific topical carbonic anhydrase inhibitors (CAIs). They lower intraocular pressure (IOP) by reducing the rate of aqueous humour formation without serious side effects. Although systemic CAIs are the most potent medications for lowering intraocular pressure for conditions with ocular hypertension, many cases with adverse systemic reactions have been re...
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Vol. 26 No. 5, 2014 645 Received December 7, 2012, Revised September 7, 2013, Accepted for publication October 5, 2013 Corresponding author: Jin-Wou Kim, Department of Dermatology, The Catholic University of Korea, Uijeongbu St. Mary’s Hospital, 271 Cheonbo-ro, Uijeongbu 480-717, Korea. Tel: 82-31-820-3031, Fax: 82-31-846-4799, E-mail: jwkim52@ catholic.ac.kr This is an Open Access article dist...
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© 2010 The Authors. doi: 10.2340/00015555-0912 Journal Compilation © 2010 Acta Dermato-Venereologica. ISSN 0001-5555 Toxic epidermal necrolysis (TEN) is a severe episodic mucocutaneous reaction due largely to ingested drugs and/or occasionally to infections. TEN presents as sheets of erythema, necrosis and bullous detachment of the epidermis, with a mortality rate of 30–35% (1). The most common...
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ژورنال
عنوان ژورنال: Annals of Dermatology
سال: 2008
ISSN: 1013-9087,2005-3894
DOI: 10.5021/ad.2008.20.4.260